Carbon Monoxide Incompletely Prevents Isoflurane-induced Defects in Murine Neurodevelopment

BACKGROUND: Commonly used anesthetics have been shown to disrupt neurodevelopment in preclinical models. It has been proposed that such anesthesia-induced neurotoxicity is mediated by apoptotic neurodegeneration in the immature brain. Low dose carbon monoxide (CO) exerts cytoprotective properties an...

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Gepubliceerd in:Neurotoxicol Teratol
Hoofdauteurs: Wang, Li, Wang, Aili, Supplee, William W., Koffler, Kayla, Cheng, Ying, Quezado, Zenaide M. N., Levy, Richard J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498225/
https://ncbi.nlm.nih.gov/pubmed/28131877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2017.01.004
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