Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases

BACKGROUND: Since leprosy is both treated and controlled by multidrug therapy (MDT) it is important to monitor recurrent cases for drug resistance and to distinguish between relapse and reinfection as a means of assessing therapeutic efficacy. All three objectives can be reached with single nucleoti...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Stefani, Mariane M. A., Avanzi, Charlotte, Bührer-Sékula, Samira, Benjak, Andrej, Loiseau, Chloé, Singh, Pushpendra, Pontes, Maria A. A., Gonçalves, Heitor S., Hungria, Emerith M., Busso, Philippe, Piton, Jérémie, Silveira, Maria I. S., Cruz, Rossilene, Schetinni, Antônio, Costa, Maurício B., Virmond, Marcos C. L., Diorio, Suzana M., Dias-Baptista, Ida M. F., Rosa, Patricia S., Matsuoka, Masanori, Penna, Maria L. F., Cole, Stewart T., Penna, Gerson O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498066/
https://ncbi.nlm.nih.gov/pubmed/28617800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005598
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