Glucose metabolism‐targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor‐induced drug‐tolerant persisters

In pathway‐targeted cancer drug therapies, the relatively rapid emergence of drug‐tolerant persisters (DTPs) substantially limits the overall therapeutic benefit. However, little is known about the roles of DTPs in drug resistance. In this study, we investigated the features of epidermal growth fact...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Kunimasa, Kei, Nagano, Tatsuya, Shimono, Yohei, Dokuni, Ryota, Kiriu, Tatsunori, Tokunaga, Shuntaro, Tamura, Daisuke, Yamamoto, Masatsugu, Tachihara, Motoko, Kobayashi, Kazuyuki, Satouchi, Miyako, Nishimura, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497794/
https://ncbi.nlm.nih.gov/pubmed/28445002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.13266
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