Novel androgen receptor co-regulator GRHL2 exerts both oncogenic and anti-metastatic functions in prostate cancer

Alterations to the expression and activity of androgen receptor (AR) co-regulators in prostate cancer is an important mechanism driving disease progression and therapy resistance. Using a novel proteomic technique, we identified a new AR co-regulator, the transcription factor Grainyhead-like 2 (GRHL...

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Publicat a:Cancer Res
Autors principals: Paltoglou, Steve, Das, Rajdeep, Townley, Scott L., Hickey, Theresa E., Tarulli, Gerard A., Coutinho, Isabel, Fernandes, Rayzel, Hanson, Adrienne R., Denis, Iza, Carroll, Jason S., Dehm, Scott M., Raj, Ganesh V., Plymate, Stephen R., Tilley, Wayne D., Selth, Luke A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5497757/
https://ncbi.nlm.nih.gov/pubmed/28473532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-1616
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