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Involvement of the Renin Angiotensin System in the Development of Nephrogenic Systemic Fibrosis-like Lesions in the RenTag Mouse Model
BACKGROUND: Renin-angiotensin system (RAS) activation increases angiotensin II production which stimulates profibrotic factors especially in the setting of chronic kidney disease. Nephrogenic systemic fibrosis (NSF) is associated with gadolinium (Gd) exposure and renal failure. RAS involvement in NS...
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| Publicado en: | Clin Exp Nephrol |
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| Autores principales: | , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5497566/ https://ncbi.nlm.nih.gov/pubmed/26138357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10157-015-1141-z |
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