A Novel Derivative of (-)mycousnine Produced by the Endophytic Fungus Mycosphaerella nawae, Exhibits High and Selective Immunosuppressive Activity on T Cells

An endophytic fungus, Mycosphaerella nawae ZJLQ129, was isolated from the leaves of the traditional Chinese medicine Smilax china. From the fermentation broth and mycelium, a dibenzofurane compound (-)mycousnine (1) was isolated. Chemical modification of it to the amide derivative (-)mycousnine enam...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Wang, Li-Wei, Wang, Jin-Liang, Chen, Jing, Chen, Jia-Jie, Shen, Jia-Wei, Feng, Xiao-Xiao, Kubicek, Christian P., Lin, Fu-Cheng, Zhang, Chu-Long, Chen, Feng-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496962/
https://ncbi.nlm.nih.gov/pubmed/28725220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01251
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