Anti-leukemia efficacy and mechanisms of action of SL-101, a novel anti-CD123 antibody-conjugate, in acute myeloid leukemia

PURPOSE: The persistence of leukemia stem cells (LSC)-containing cells after induction therapy may contribute to minimal residual disease (MRD) and relapse in acute myeloid leukemia (AML). We investigated the clinical relevance of CD34(+)CD123(+) LSC-containing cells and anti-leukemia potency of a n...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Han, Lina, Jorgensen, Jeffrey L, Brooks, Chris, Shi, Ce, Zhang, Qi, Nogueras González, Graciela M., Cavazos, Antonio, Pan, Rongqing, Mu, Hong, Wang, Sa A, Zhou, Jin, AI-Atrash, Gheath, Ciurea, Stefan O., Rettig, Mike, DiPersio, John F., Cortes, Jorge, Huang, Xuelin, Kantarjian, Hagop M, Andreeff, Michael, Ravandi, Farhad, Konopleva, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496806/
https://ncbi.nlm.nih.gov/pubmed/28096272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1904
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados