Expression of CD14, IL-10 and tolerogenic signature in dendritic cells inversely correlate with clinical and immunological response to TARP vaccination in prostate cancer patients

PURPOSE: Despite the vast number of clinical trials conducted so far, Dendritic cell (DC)-based cancer vaccines have mostly shown unsatisfactory results. Factors and manufacturing procedures essential for these therapeutics to induce effective anti-tumor immune responses have yet to be fully charact...

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Bibliografske podrobnosti
izdano v:Clin Cancer Res
Main Authors: Castiello, Luciano, Sabatino, Marianna, Ren, Jiaqiang, Terabe, Masaki, Khuu, Hanh, Wood, Lauren V, Berzofsky, Jay A, Stroncek, David F
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496805/
https://ncbi.nlm.nih.gov/pubmed/28073842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2199
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