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Unsupervised clustering of quantitative image phenotypes reveals breast cancer subtypes with distinct prognoses and molecular pathways

PURPOSE: To identify novel breast cancer subtypes by extracting quantitative imaging phenotypes of the tumor and surrounding parenchyma, and to elucidate the underlying biological underpinnings and evaluate the prognostic capacity for predicting recurrence-free survival (RFS). METHODS: We retrospect...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Wu, Jia, Cui, Yi, Sun, Xiaoli, Cao, Guohong, Li, Bailiang, Ikeda, Debra M., Kurian, Allison W., Li, Ruijiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496801/
https://ncbi.nlm.nih.gov/pubmed/28073839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2415
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