Bombesin Antagonist Based Radiotherapy of Prostate Cancer Combined with WST-11 Vascular Targeted Photodynamic Therapy

PURPOSE: DOTA-AR, a bombesin-antagonist peptide, has potential clinical application for targeted imaging and therapy in Gastrin Releasing Peptide receptor (GRPr) positive malignancies when conjugated with a radioisotope such as (90)Y. This therapeutic potential is limited by the fast washout of the...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Kim, Kwanghee, Zhang, Hanwen, La Rosa, Stephen, Jebiwott, Sylvia, Desai, Pooja, Kimm, Simon, Scherz, Avigdor, O’Donoghue, Joseph A, Weber, Wolfgang A, Coleman, Jonathan A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496795/
https://ncbi.nlm.nih.gov/pubmed/28108545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-2745
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