ILC2s are recruited to nasal mucosa in aspirin-exacerbated respiratory disease

BACKGROUND: Aspirin-exacerbated respiratory disease (AERD) is characterized by tissue eosinophilia and mast cell activation, including abundant production of prostaglandin D2 (PGD2). Group 2 innate lymphoid cells (ILC2s), which promote tissue eosinophilia and mast cell responses, undergo chemotaxis...

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Udgivet i:J Allergy Clin Immunol
Main Authors: Eastman, Jacqueline J., Cavagnero, Kellen J., Deconde, Adam S., Kim, Alex S., Karta, Maya R., Broide, David H., Zuraw, Bruce L., White, Andrew A., Christiansen, Sandra C., Doherty, Taylor A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496786/
https://ncbi.nlm.nih.gov/pubmed/28279492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.11.023
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