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MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial to Mesenchymal Transition
The first epithelial to mesenchymal transition (EMT) occurs in trophoblast stem (TS) cells during implantation. Inactivation of the serine/threonine kinase MAP3K4 in TS cells (TS(KI4) cells) induces an intermediate state of EMT, where cells retain stemness, lose epithelial markers, and gain mesenchy...
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| Veröffentlicht in: | Cell Rep |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496714/ https://ncbi.nlm.nih.gov/pubmed/28273454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.030 |
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