MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial to Mesenchymal Transition

The first epithelial to mesenchymal transition (EMT) occurs in trophoblast stem (TS) cells during implantation. Inactivation of the serine/threonine kinase MAP3K4 in TS cells (TS(KI4) cells) induces an intermediate state of EMT, where cells retain stemness, lose epithelial markers, and gain mesenchy...

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Udgivet i:Cell Rep
Main Authors: Mobley, Robert J., Raghu, Deepthi, Duke, Lauren D., Abell-Hart, Kayley, Zawistowski, Jon S., Lutz, Kyla, Gomez, Shawn M., Roy, Sujoy, Homayouni, Ramin, Johnson, Gary L., Abell, Amy N.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496714/
https://ncbi.nlm.nih.gov/pubmed/28273454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.030
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