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Ccdc181 is a microtubule binding protein that interacts with Hook1 in haploid male germ cells and localizes to the sperm tail and motile cilia
Disruption of murine Hook1 results in a disturbed spermatogenesis and consequently leads to male infertility in mice. Within these mice abnormal sperm development starts with a disorganization of the microtubular manchette in elongating spermatids that leads to an abnormal head shape as well as to d...
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Publicado no: | Eur J Cell Biol |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5496667/ https://ncbi.nlm.nih.gov/pubmed/28283191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2017.02.003 |
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