Nasal administration of the neuroprotective candidate NeuroEPO to healthy volunteers: a randomized, parallel, open-label safety study

BACKGROUND: Delivery of therapeutic agents as erythropoietin (EPO) into Central Nervous System through intranasal route could benefit patients with neurological disorders. A new nasal formulation containing a non-hematopoietic recombinant EPO (NeuroEPO) has shown neuroprotective actions in preclinic...

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Detalhes bibliográficos
Publicado no:BMC Neurol
Main Authors: Santos-Morales, Orestes, Díaz-Machado, Alina, Jiménez-Rodríguez, Daise, Pomares-Iturralde, Yaisel, Festary-Casanovas, Tatiana, González-Delgado, Carlos A., Pérez-Rodríguez, Sonia, Alfonso-Muñoz, Eulalia, Viada-González, Carmen, Piedra-Sierra, Patricia, García-García, Idrian, Amaro-González, Daniel, García-Rodríguez, Julio César, Sosa-Testé, Iliana, Lagarto-Parra, Alicia, Barrero-Viera, Laura, David-Baldo, Marlene, Tamayo-Rodríguez, Maura, Rivero-Vázquez, Ivonne, González-Gamiz, Gricel, Martín-Trujillo, Alis, Rodríguez-Fernández, Yasmila, Ledo-de la Luz, Ana Alfa, Álvarez-Delgado, Maylén, Howland-Álvarez, Ivón, Cruz-Gómez, Yolanda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496637/
https://ncbi.nlm.nih.gov/pubmed/28676085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12883-017-0908-0
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