Characterization of Lgr5+ Progenitor Cell Transcriptomes after Neomycin Injury in the Neonatal Mouse Cochlea

Lgr5+ supporting cells (SCs) are enriched hair cell (HC) progenitors in the cochlea. Both in vitro and in vivo studies have shown that HC injury can spontaneously activate Lgr5+ progenitors to regenerate HCs in the neonatal mouse cochlea. Promoting HC regeneration requires the understanding of the m...

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Publicado en:Front Mol Neurosci
Autores principales: Zhang, Shasha, Zhang, Yuan, Yu, Pengfei, Hu, Yao, Zhou, Han, Guo, Lingna, Xu, Xiaochen, Zhu, Xiaocheng, Waqas, Muhammad, Qi, Jieyu, Zhang, Xiaoli, Liu, Yan, Chen, Fangyi, Tang, Mingliang, Qian, Xiaoyun, Shi, Haibo, Gao, Xia, Chai, Renjie
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496572/
https://ncbi.nlm.nih.gov/pubmed/28725177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2017.00213
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