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Longitudinal MR spectroscopy of neurodegeneration in multiple sclerosis with diffusion of the intra-axonal constituent N-acetylaspartate

Multiple sclerosis (MS) is a pathologically complex CNS disease: inflammation, demyelination, and neuroaxonal degeneration occur concurrently and may depend on one another. Current therapies are aimed at the immune-mediated, inflammatory destruction of myelin, whereas axonal degeneration is ongoing...

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Detalhes bibliográficos
Publicado no:Neuroimage Clin
Main Authors: Wood, Emily Turner, Ercan, Ece, Sati, Pascal, Cortese, Irene C.M., Ronen, Itamar, Reich, Daniel S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496488/
https://ncbi.nlm.nih.gov/pubmed/28702353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2017.06.028
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