Potent long-acting rhFGF21 analog for treatment of diabetic nephropathy in db/db and DIO mice

BACKGROUND: Fibroblast growth factor 21 (FGF21) is an endocrine-acting hormone that has the potential to treat diabetic nephropathy. However, development of FGF21 into a therapeutic has been hindered due to its low intrinsic bio-stability. In our previous study, we have developed a recombinant human...

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Detaylı Bibliyografya
Yayımlandı:BMC Biotechnol
Asıl Yazarlar: Zhao, Longwei, Wang, Huiyan, Xie, Junjun, Chen, Zilu, Li, Xiaokun, Niu, Jianlou
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496364/
https://ncbi.nlm.nih.gov/pubmed/28676059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-017-0368-z
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