Effect of pharmacogenetics on plasma lumefantrine pharmacokinetics and malaria treatment outcome in pregnant women

BACKGROUND: Pregnancy has considerable effects on the pharmacokinetic properties of drugs used to treat uncomplicated Plasmodium falciparum malaria. The role of pharmacogenetic variation on anti-malarial drug disposition and efficacy during pregnancy is not well investigated. The study aimed to exam...

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Detalhes bibliográficos
Publicado no:Malar J
Main Authors: Mutagonda, Ritah F., Kamuhabwa, Appolinary A. R., Minzi, Omary M. S., Massawe, Siriel N., Asghar, Muhammad, Homann, Manijeh V., Färnert, Anna, Aklillu, Eleni
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496343/
https://ncbi.nlm.nih.gov/pubmed/28673292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-017-1914-9
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