Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.

In the murine myelomonocytic leukemia WEHI-3B, proviral insertions have induced expression of the Hox-2.4 homeobox gene and the gene for the myeloid growth factor interleukin 3 (IL-3). To assess their potential oncogenic role, normal bone marrow cells were infected with retroviruses bearing the gene...

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Autores principales: Perkins, A, Kongsuwan, K, Visvader, J, Adams, J M, Cory, S
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC54963/
https://ncbi.nlm.nih.gov/pubmed/1978323
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