Cantharidin suppressed breast cancer MDA-MB-231 cell growth and migration by inhibiting MAPK signaling pathway

As an active constituent of the beetle Mylabris used in traditional Chinese medicine, cantharidin is a potent and selective inhibitor of protein phosphatase 2A (PP2A) that plays a crucial role in cell cycle progression, apoptosis, and cell fate. The role and possible mechanisms exerted by cantharidi...

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Bibliografiske detaljer
Udgivet i:Braz J Med Biol Res
Main Authors: Gu, X.-D., Xu, L.-L, Zhao, H., Gu, J.-Z, Xie, X.-H
Format: Artigo
Sprog:Inglês
Udgivet: Associação Brasileira de Divulgação Científica 2017
Fag:
Biomedical Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496155/
https://ncbi.nlm.nih.gov/pubmed/28678918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20175920
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