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Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export
The mRNA export adaptor Yra1p/REF contributes to nascent mRNP assembly and recruitment of the export receptor Mex67p. yra1 mutants exhibit mRNA export defects and a decrease in LacZ reporter and certain endogenous transcripts. The loss of Mlp1p/Mlp2p, two TPR-like proteins attached to nuclear pores,...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549612/ https://ncbi.nlm.nih.gov/pubmed/15692572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600527 |
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