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Sodium selenate treatment improves symptoms and seizure susceptibility in a malin-deficient mouse model of Lafora disease
OBJECTIVE: To search for new therapies aimed at ameliorating the neurologic symptoms and epilepsy developing in patients with Lafora disease. METHODS: Lafora disease is caused by loss-of-function mutations in either the EPM2A or EPM2B genes. Epm2a(−/−) and Epm2b(−/−) mice display neurologic and beha...
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| Publicado no: | Epilepsia |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495962/ https://ncbi.nlm.nih.gov/pubmed/28098937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13656 |
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