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Endothelial dysfunction inhibits the ability of haptoglobin to prevent hemoglobin-induced hypertension
Intravascular hemolysis produces injury in a variety of human diseases including hemoglobinopathies, malaria, and sepsis. The adverse effects of increased plasma hemoglobin are partly mediated by depletion of nitric oxide (NO) and result in vasoconstriction. Circulating plasma proteins haptoglobin a...
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| Publicado no: | Am J Physiol Heart Circ Physiol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495929/ https://ncbi.nlm.nih.gov/pubmed/28314763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00851.2016 |
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