Evidence for intraventricular secretion of angiotensinogen and angiotensin by the subfornical organ using transgenic mice

Direct intracerebroventricular injection of angiotensin II (ANG II) causes increases in blood pressure and salt and water intake, presumably mimicking an effect mediated by an endogenous mechanism. The subfornical organ (SFO) is a potential source of cerebrospinal fluid (CSF), ANG I, and ANG II, and...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Agassandian, Khristofor, Grobe, Justin L., Liu, Xuebo, Agassandian, Marianna, Thompson, Anthony P., Sigmund, Curt D., Cassell, Martin D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495920/
https://ncbi.nlm.nih.gov/pubmed/28490451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00511.2016
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