Gremlin1 plays a key role in kidney development and renal fibrosis

Gremlin1 (Grem1), an antagonist of bone morphogenetic proteins, plays a key role in embryogenesis. A highly specific temporospatial gradient of Grem1 and bone morphogenetic protein signaling is critical to normal lung, kidney, and limb development. Grem1 levels are increased in renal fibrotic condit...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Renal Physiol
Main Authors: Church, Rachel H., Ali, Imran, Tate, Mitchel, Lavin, Deborah, Krishnakumar, Arjun, Kok, Helena M., Hombrebueno, Jose R., Dunne, Philip D., Bingham, Victoria, Goldschmeding, Roel, Martin, Finian, Brazil, Derek P.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495891/
https://ncbi.nlm.nih.gov/pubmed/28100499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00344.2016
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