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Opportunistic Pathogen Porphyromonas gingivalis Modulates Danger Signal ATP-Mediated Antibacterial NOX2 Pathways in Primary Epithelial Cells

Porphyromonas gingivalis, a major opportunistic pathogen in the etiology of chronic periodontitis, successfully survives in human gingival epithelial cells (GECs). P. gingivalis abrogates the effects of a host danger molecule, extracellular ATP (eATP)/P2X(7) signaling, such as the generation of reac...

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Bibliographic Details
Published in:Front Cell Infect Microbiol
Main Authors: Roberts, JoAnn S., Atanasova, Kalina R., Lee, Jungnam, Diamond, Gill, Deguzman, Jeff, Hee Choi, Chul, Yilmaz, Özlem
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495830/
https://ncbi.nlm.nih.gov/pubmed/28725637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2017.00291
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