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Pancreatic cancer: Circulating Tumor Cells and Primary Tumors show Heterogeneous KRAS Mutations

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease. Circulating tumor cells (CTC) in the blood are hypothesized as the means of systemic tumor spread. Blood obtained from healthy donors and patients with PDAC was therefore subject to size-based CTC-isolation. We additionally compared K...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kulemann, Birte, Rösch, Stephanie, Seifert, Sindy, Timme, Sylvia, Bronsert, Peter, Seifert, Gabriel, Martini, Verena, Kuvendjiska, Jasmina, Glatz, Torben, Hussung, Saskia, Fritsch, Ralph, Becker, Heiko, Pitman, Martha B., Hoeppner, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495768/
https://ncbi.nlm.nih.gov/pubmed/28674438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04601-z
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