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Differential Regulation of Intestinal Efflux Transporters by Pregnancy in Mice

1. In the intestines, the nuclear receptors Fxr and Pxr regulate the transcription of metabolizing enzymes and transporters that dictate the absorption of nutrients and xenobiotics. 2. Here, we sought to determine whether Fxr and Pxr signaling pathways are disrupted in response to high circulating c...

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Sonraí Bibleagrafaíochta
Foilsithe in:Xenobiotica
Main Authors: Moscovitz, Jamie E, Yarmush, Gabriel, Herrera-Garcia, Guadalupe, Guo, Grace L., Aleksunes, Lauren M
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495628/
https://ncbi.nlm.nih.gov/pubmed/28043194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/00498254.2016.1250292
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