Troglitazone, a PPAR-γ activator prevents endothelial cell adhesion molecule expression and lymphocyte adhesion mediated by TNF-α

BACKGROUND: Cytokine mediated induction of the mucosal addressin cell adhesion molecule-1(MAdCAM-1) expression is associated with the onset and progression of inflammatory bowel disease (IBD). RESULTS: Using western blotting and cell-based ELISA, we show in this study that troglitazone, an activator...

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Detalhes bibliográficos
Main Authors: Sasaki, Makoto, Jordan, Paul, Welbourne, Tomas, Minagar, Alireza, Joh, Takashi, Itoh, Makoto, Elrod, John W, Alexander, J Steven
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC549552/
https://ncbi.nlm.nih.gov/pubmed/15694007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6793-5-3
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