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In- and ex-vivo molecular imaging of apoptosis to assess sensitivity of non-small cell lung cancer to EGFR inhibitors using probe-based confocal laser endomicroscopy

BACKGROUND: Prediction of treatment outcome of non-small cell lung cancer (NSCLC) with EGFR inhibitors on the basis of the genetic analysis of the tumor can be incorrect in case of rare or complex mutations, bypass molecular activation pathways, or pharmacodynamic variations. The aim of this study w...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Guisier, Florian, Bohn, Pierre, Patout, Maxime, Piton, Nicolas, Farah, Insaf, Vera, Pierre, Thiberville, Luc, Salaün, Mathieu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495425/
https://ncbi.nlm.nih.gov/pubmed/28671975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180576
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