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Retroviral host range extension is coupled with Env-activating mutations resulting in receptor-independent entry

The extent of virus transmission among individuals and species is generally determined by the presence of specific membrane-embedded virus receptors required for virus entry. Interaction of the viral envelope glycoprotein (Env) with a specific cellular receptor is the first and crucial step in deter...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Lounková, Anna, Kosla, Jan, Přikryl, David, Štafl, Kryštof, Kučerová, Dana, Svoboda, Jan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495266/
https://ncbi.nlm.nih.gov/pubmed/28607078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1704750114
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