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Regulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIβ

Dendritic spines of Purkinje cells form excitatory synapses with parallel fiber terminals, which are the primary sites for cerebellar synaptic plasticity. Nevertheless, how density and morphology of these spines are properly maintained in mature Purkinje cells is not well understood. Here we show an...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Sugawara, Takeyuki, Hisatsune, Chihiro, Miyamoto, Hiroyuki, Ogawa, Naoko, Mikoshiba, Katsuhiko
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495224/
https://ncbi.nlm.nih.gov/pubmed/28607044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617270114
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