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Aspergillus fumigatus CalA Binds to Integrin α5β1 and Mediates Host Cell Invasion

The opportunistic fungal pathogen, Aspergillus fumigatus invades pulmonary epithelial cells and vascular endothelial cells by inducing its own endocytosis, but the mechanism by which this process occurs is poorly understood. Here, we show that the thaumatin-like protein CalA is expressed on the surf...

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Detalhes bibliográficos
Publicado no:Nat Microbiol
Main Authors: Liu, Hong, Lee, Mark J., Solis, Norma V., Phan, Quynh T., Swidergall, Marc, Ralph, Benjamin, Ibrahim, Ashraf S., Sheppard, Donald C., Filler, Scott G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495140/
https://ncbi.nlm.nih.gov/pubmed/27841851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.211
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