Identification of a Novel Epoxyqueuosine Reductase Family by Comparative Genomics

[Image: see text] The reduction of epoxyqueuosine (oQ) is the last step in the synthesis of the tRNA modification queuosine (Q). While the epoxyqueuosine reductase (EC 1.17.99.6) enzymatic activity was first described 30 years ago, the encoding gene queG was only identified in Escherichia coli in 20...

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Udgivet i:ACS Chem Biol
Main Authors: Zallot, Rémi, Ross, Robert, Chen, Wei-Hung, Bruner, Steven D., Limbach, Patrick A., de Crécy-Lagard, Valérie
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495094/
https://ncbi.nlm.nih.gov/pubmed/28128549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.6b01100
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