Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

The 3D organization of the genome changes concomitantly with expression changes during hematopoiesis and immune activation. Studies have focused either on lamina-associated domains (LADs) or on topologically associated domains (TADs), defined by preferential local chromatin interactions, and chromos...

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Publicado en:Genome Res
Autores principales: Robson, Michael I., de las Heras, Jose I., Czapiewski, Rafal, Sivakumar, Aishwarya, Kerr, Alastair R.W., Schirmer, Eric C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495065/
https://ncbi.nlm.nih.gov/pubmed/28424353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.212308.116
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