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Two different, mutually exclusively distributed, TP53 mutations in ovarian and peritoneal tumor tissues of a serous ovarian cancer patient: indicative for tumor origin?

High-grade serous ovarian cancer (HGSOC) is characterized by a TP53 mutation rate of up to 96.7% and associated with a more aggressive tumor biology. The origin of HGSOC is thought to arise either from fallopian tube secretory cells or the ovarian surface epithelium/inclusion cysts, the former with...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cold Spring Harb Mol Case Stud
Main Authors: Sukhbaatar, Nyamdelger, Bachmayr-Heyda, Anna, Auer, Katharina, Aust, Stefanie, Deycmar, Simon, Horvat, Reinhard, Pils, Dietmar
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5495036/
https://ncbi.nlm.nih.gov/pubmed/28679689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a001461
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