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Identification of a gene that positively regulates expression of listeriolysin, the major virulence factor of listeria monocytogenes.

We have isolated, by molecular cloning and genetic complementation of a listeriolysin-negative mutant, a gene required for the expression of this virulence factor in Listeria monocytogenes. The mutant strain SLCC53, which was nonhemolytic and avirulent, harbored a deletion of 450 base pairs located...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Leimeister-Wächter, M, Haffner, C, Domann, E, Goebel, W, Chakraborty, T
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54950/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2122460/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8336
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