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Characterization of CD56(–)/CD16(+) natural killer (NK) cells: A highly dysfunctional NK subset expanded in HIV-infected viremic individuals

Natural killer (NK) cells are an important component of the innate immune response against viral infections. NK cell-mediated cytolytic activity is defective in HIV-infected individuals with high levels of viral replication. In the present study, we examined the phenotypic and functional characteris...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Mavilio, Domenico, Lombardo, Gabriella, Benjamin, Janet, Kim, Diana, Follman, Dean, Marcenaro, Emanuela, O'Shea, M. Angeline, Kinter, Audrey, Kovacs, Colin, Moretta, Alessandro, Fauci, Anthony S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
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Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC549494/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15699323/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0409872102
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