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Methylation-Specific Multiplex Ligation-Dependent Probe Amplification Analysis of Subjects with Chromosome 15 Abnormalities

Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are neurodevelopmental disorders caused by loss of expression of imprinted genes from the 15q11-q13 region. They arise from similar defects in the region but differ in parent of origin. There are two recognized typical 15q11-q13 deletions depend...

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Detalhes bibliográficos
Publicado no:Genet Test
Main Authors: BITTEL, DOUGLAS C., KIBIRYEVA, NATALIYA, BUTLER, MERLIN G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494700/
https://ncbi.nlm.nih.gov/pubmed/18294067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gte.2007.0061
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