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Metformin enhances the cytotoxicity of 5-aminolevulinic acid-mediated photodynamic therapy in vitro

The biguanide metformin is a drug widely used for the treatment of type 2 diabetes. Metformin enhances the cytotoxicity of chemotherapy by promoting the adenosine monophosphate-activated protein kinase (AMPK) autophagy signaling pathway. Photodynamic therapy (PDT) with 5-aminolevulinic acid (5-ALA),...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Osaki, Tomohiro, Yokoe, Inoru, Takahashi, Kiwamu, Inoue, Katsushi, Ishizuka, Masahiro, Tanaka, Tohru, Azuma, Kazuo, Murahata, Yusuke, Tsuka, Takeshi, Itoh, Norihiko, Imagawa, Tomohiro, Okamoto, Yoshiharu
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5494612/
https://ncbi.nlm.nih.gov/pubmed/28693272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.6237
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