Evidence for involvement of multiple forms of cytochrome P-450 in aflatoxin B1 metabolism in human liver.

Liver cancer is a major cause of premature death in many areas of Africa and Asia and its incidence is strongly correlated with exposure to aflatoxin B1 (AFB1). Because AFB1 requires metabolic activation to achieve a biological response, there is a need for detailed knowledge of the mechanism of act...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Forrester, L M, Neal, G E, Judah, D J, Glancey, M J, Wolf, C R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54944/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2122459/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8306
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