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Design of nucleic acid sequences for DNA computing based on a thermodynamic approach
We have developed an algorithm for designing multiple sequences of nucleic acids that have a uniform melting temperature between the sequence and its complement and that do not hybridize non-specifically with each other based on the minimum free energy (ΔG(min)). Sequences that satisfy these constra...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549402/ https://ncbi.nlm.nih.gov/pubmed/15701762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki235 |
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