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Design of nucleic acid sequences for DNA computing based on a thermodynamic approach

We have developed an algorithm for designing multiple sequences of nucleic acids that have a uniform melting temperature between the sequence and its complement and that do not hybridize non-specifically with each other based on the minimum free energy (ΔG(min)). Sequences that satisfy these constra...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Tanaka, Fumiaki, Kameda, Atsushi, Yamamoto, Masahito, Ohuchi, Azuma
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC549402/
https://ncbi.nlm.nih.gov/pubmed/15701762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki235
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