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Toxin–antitoxin loci are highly abundant in free-living but lost from host-associated prokaryotes

Prokaryotic chromosomes code for toxin–antitoxin (TA) loci, often in multiple copies. In E.coli, experimental evidence indicates that TA loci are stress-response elements that help cells survive unfavorable growth conditions. The first gene in a TA operon codes for an antitoxin that combines with an...

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Bibliografiske detaljer
Main Authors: Pandey, Deo Prakash, Gerdes, Kenn
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC549392/
https://ncbi.nlm.nih.gov/pubmed/15718296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki201
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