Adult T-cell leukemia-derived factor/thioredoxin, produced by both human T-lymphotropic virus type I- and Epstein-Barr virus-transformed lymphocytes, acts as an autocrine growth factor and synergizes with interleukin 1 and interleukin 2.

Interleukin 1 (IL-1) has been obtained from the Epstein-Barr virus-infected B-lymphoblastoid cell line 3B6 and shown to be involved in autocrine growth of 3B6 B cells. Independently, adult T-cell leukemia-derived factor (ADF) was purified from human T-lymphotropic virus I-infected leukemic T-cell li...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Wakasugi, N, Tagaya, Y, Wakasugi, H, Mitsui, A, Maeda, M, Yodoi, J, Tursz, T
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54939/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2172979/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.21.8282
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