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The Hippo pathway acts downstream of the Hedgehog signaling to regulate follicle stem cell maintenance in the Drosophila ovary

The Hippo pathway is conserved and plays important roles in organ size control. The core components of the Hippo pathway are two kinases Hippo (Hpo), Warts (Wts), and a transcription-co-activator Yorkie (Yki). Yki activity is regulated by phosphorylation, which affects its nuclear localization and s...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Hsu, Ta-Hsing, Yang, Chia-Yu, Yeh, Tsung-Han, Huang, Yi-Chia, Wang, Tsu-Wei, Yu, Jenn-Yah
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493701/
https://ncbi.nlm.nih.gov/pubmed/28667262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04052-6
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