Genetic Deletion of the Repressor of Estrogen Receptor Activity (REA) Enhances the Response to Estrogen in Target Tissues In Vivo

We previously identified a coregulator, repressor of estrogen receptor activity (REA), that directly interacts with estrogen receptor (ER) and represses ER transcriptional activity. Decreasing the intracellular level of REA by using small interfering RNA knockdown or antisense RNA approaches in cell...

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Détails bibliographiques
Auteurs principaux: Park, Seong-Eun, Xu, Jianming, Frolova, Antonina, Liao, Lan, O'Malley, Bert W., Katzenellenbogen, Benita S.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC549370/
https://ncbi.nlm.nih.gov/pubmed/15713652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1989-1999.2005
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