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Opposing Effects of Polyadenylation on the Stability of Edited and Unedited Mitochondrial RNAs in Trypanosoma brucei

Mitochondrial RNAs in Trypanosoma brucei undergo posttranscriptional RNA editing and polyadenylation. We previously showed that polyadenylation stimulates turnover of unedited RNAs. Here, we investigated the role of polyadenylation in decay of edited RPS12 RNA. In in vitro turnover assays, nonadenyl...

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Autors principals: Kao, Chia-Ying, Read, Laurie K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549368/
https://ncbi.nlm.nih.gov/pubmed/15713623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1634-1644.2005
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