Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (GTKO.hCD4...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Bongoni, Anjan K., Salvaris, Evelyn, Nordling, Sofia, Klymiuk, Nikolai, Wolf, Eckhard, Ayares, David L., Rieben, Robert, Magnusson, Peetra U., Cowan, Peter J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493627/
https://ncbi.nlm.nih.gov/pubmed/28667310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04898-w
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