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Maspin Mediates Increased Tumor Cell Apoptosis upon Induction of the Mitochondrial Permeability Transition

Maspin is a unique serpin with the ability to suppress certain types of malignant tumors. It is one of the few p53-targeted genes involved in tumor invasion and metastasis. With this in mind, we attempted to study the molecular mechanism behind this tumor suppression. Maspin-expressing mammary tumor...

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Autores principales: Latha, Khatri, Zhang, Weiguo, Cella, Nathalie, Shi, Heidi Y., Zhang, Ming
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC549349/
https://ncbi.nlm.nih.gov/pubmed/15713631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.5.1737-1748.2005
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