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Indole-3-carbinol, a plant nutrient and AhR-Ligand precursor, supports oral tolerance against OVA and improves peanut allergy symptoms in mice

In general, dietary antigens are tolerated by the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl hydrocarbon receptor (AhR) by the environmental pollutant 2...

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Publicado en:PLoS One
Autores principales: Hammerschmidt-Kamper, Christiane, Biljes, Daniel, Merches, Katja, Steiner, Irina, Daldrup, Thomas, Bol-Schoenmakers, Marianne, Pieters, Raymond H. H., Esser, Charlotte
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5493375/
https://ncbi.nlm.nih.gov/pubmed/28666018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180321
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